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So far, it does seem that a chemo cycle with paclitaxel is less taxing on my body than the AC cycles. To help prevent a serious allergic reaction to paclitaxel, I took dexamethasone 12 hours and 6 hours before treatment. If you're going to have a serious allergic reaction, it is usually during the first or second treatment, and will happen within the first 30 minutes. I didn't have any issues after the first treatment, so hopefully there won't be any allergy issues going forward. Dexamethasone did made it harder to sleep for the first couple nights, and then muscle aches made it hard to do much (including sleep) for several days after chemo. Tylenol didn't help much, but heating pads provided some relief and doing some walking also seemed to help. I also developed tingling in my feet that has gotten better over this cycle but hasn't fully gone away. The chemo nurse also said that paclitaxel can be more irritating to the local vein when administered by IV, so there a...